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vsprefixcleanup.exe does stop the profiler. It does not kill processes. It only cleans environment variables for the current process and any future children spawned after cleanup.
The Hidden Workhorse: Understanding vsprecleanvs.exe in Visual Studio 2012 vsprecleanvsexe visual studio 2012 exclusive
Projects with custom pre-build events that invoke tools (e.g., copy , xcopy , or file transformers) might not release file handles properly before VS’s clean step runs. vsprefixcleanup
vsprefixcleanup.exe is a much more specialized tool. Its sole function is to from the current process and its child processes. These variables are typically prefixed with: vsprecleanvsexe visual studio 2012 exclusive